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What Are the Side Effects of Protonix?


Updated December 07, 2010

Written or reviewed by a board-certified physician. See About.com's Medical Review Board.

Question: What Are the Side Effects of Protonix?

Many patients taking Protonix don't experience any side effects. Others may experience minor side effects that are either minor and disappear within a few days, or are easily treated. As with any side effects with any medications, if they persist or become severe, you should contact your doctor.

  • upset stomach
  • headache
  • diarrhea
  • constipation
  • stomach pain
  • cough
  • mild rash
  • back, neck, or joint pain

If you experience any of the following symptoms, call your doctor immediately:

  • chest pain
  • difficulty breathing or swallowing
  • itching
  • weakness
  • rash or hives
  • severe skin rash with swelling and peeling
  • swollen face, lower legs, or ankles
  • vision changes
  • vomiting
  • yellowing of skin or eyes
  • fever
  • confusion
  • slow movements
  • speech problems
  • increased salivation
  • difficulty maintaining balance
  • ringing in the ears
  • sinus or upper respiratory tract infection

Protonix may cause hyperglycemia (high blood sugar). If you have any of the following symptoms, call your doctor immediately:

  • thirst
  • dry mouth
  • tiredness
  • flushing
  • dry skin
  • frequent urination
  • lost of appetite
  • trouble breathing

There may be other side effects not listed here, so you should always contact your doctor if you have any unusual or concerning symptoms while taking this medication.

Related Information:


"Protonix." U.S. Food and Drug Administration.

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