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Side Effects of Proton Pump Inhibitors

By , About.com Guide

Updated July 29, 2011

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

Proton Pump Inhibitors (PPIs) as a class of medicine are very safe, work the same way, are roughly interchangeable, and only rarely cause severe side effects. However, because they can reduce your stomach acid, they can increase the chances of getting certain infections, and can decrease absorption of certain medicines. This is why you need to discuss these medicines with your health care provider. Lists of side effects caused by drugs need to be read with a keen eye -– they are lists of symptoms experienced by patients during clinical studies, and aren’t always common nor are they always actually caused by the medicine. Moreover, depending on how the side effect data is collected, and what type of underlying illnesses the study patients have, the detail and accuracy vary. Nevertheless, for severe side effects, and for symptoms of hives/breathing/difficulty swallowing, you should be sure to contact your health care provider immediately.

What Are the Different Types of Proton Pump Inhibitors?

The different types of PPIs include Aciphex, Dexilant, Nexium, Prevacid, Prilosec, and Protonix.

Possible Side Effects of Proton Pump Inhibitors

As mentioned above, side effects from the use of PPIs are rarely severe. If side effects do occur, they are usually mild and disappear quickly. Also, the side effects for each PPI are very similar to those of the other PPIs. To see what the side effects are for each PPI, you can check the information below:

What Are Proton Pump Inhibitors Used For?

Proton pump inhibitors are used in the treatment of GERD, peptic ulcers, erosive esophagitis, and Zollinger-Ellison syndrome. Doctors may prescribe using PPIs alone, or in combination with antacids. PPIs may also be used in combination with certain antibiotics (e.g. amoxycillin and clarithromycin) when treating Helicobacter pylori (H. pylori) infection (a bacterial infection of the stomach), which is thought to be one of the main causes of recurring stomach ulcers.

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