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Updated March 06, 2008

Generic Name:

  • Pantoprazole
Brand Names:
  • Protonix
  • Somac
  • Pantoloc
This medication is available by prescription only.

Why is Protonix prescribed?

Protonix is prescribed to used to treat GERD, erosive esophagitis associated with GERD, peptic ulcer disease (as part of combination therapy with an antibiotic to eradicate H. Pylori), and hypersecretory disorders including Zollinger-Ellison syndrome.

Special precautions to follow when taking Protonix

  • Tell your doctor and pharmacist if you are allergic to lansoprazole, omeprazole, pantoprazole, rabeprazole, or any other drugs.

  • Tell your doctor and pharmacist what prescription and nonprescription medications you are taking, vitamins and herbal products.

  • Tell your doctor if you have or have ever had liver disease.

  • Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking Protonix, call your doctor.

  • If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking Protonix.

What if you forget a dose?

Consult your physician before taking a missed dose. Your doctor will be able to determine if it is safe to do so, or if you should wait until your next scheduled dose. Do not take a double dose to make up for a missed one.

Possible side effects of Protonix

Although side effects from Protonix are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:
  • upset stomach
  • headache
  • diarrhea
  • constipation
  • stomach pain
  • cough
  • mild rash
  • back, neck, or joint pain
If you experience any of the following symptoms, call your doctor immediately:
  • chest pain
  • difficulty breathing or swallowing
  • itching
  • weakness
  • rash or hives
  • severe skin rash with swelling and peeling
  • swollen face, lower legs, or ankles
  • vision changes
  • vomiting
  • yellowing of skin or eyes
  • fever
  • confusion
  • slow movements
  • speech problems
  • increased salivation
  • difficulty maintaining balance
  • ringing in the ears
  • sinus or upper respiratory tract infection
Protonix may cause hyperglycemia (high blood sugar). If you have any of the following symptoms, call your doctor immediately:
  • thirst
  • dry mouth
  • tiredness
  • flushing
  • dry skin
  • frequent urination
  • lost of appetite
  • trouble breathing

Storage conditions needed for Protonix

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.


"Protonix." U.S. Food and Drug Administration. 11 Mar 2007

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