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H2 Blocker FAQs


Updated June 29, 2008

H2 blockers, also called H2-receptor antagonists, are medicines that reduce the amount of acid the stomach produces by blocking one important producer of acid: histamine2.

Histamine2, a common chemical in the body, signals the stomach to make acid. H2 blockers oppose histamine’s action and reduce the amount of acid the stomach produces. This type of medication is used to treat conditions in which the stomach produces too much acid, such as gastroesophageal reflux disease (GERD). They also have been prescribed for the treatment of peptic ulcer symptoms.

Below are commonly asked questions about H2 blockers.

H2 blockers include Zantac (ranitidine), Pepcid (famotidine), Tagamet (cimetidine), and Axid (nizatidine).

For more information on these medications, and others, please go to Drugs A to Z.

For more information on Gastroesophageal Reflux Disease (GERD), you can find information at the following resources:

Children and GERD:

  1. About.com
  2. Health
  3. Heartburn / GERD
  4. Meds / Remedies
  5. H2 Blockers
  6. H2 Blockers - GERD Treatment -

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