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Gastrointestinal motility disorders

By , About.com Guide

Updated June 08, 2006

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

In normal digestion, food is moved through the digestive tract by rhythmic contractions called peristalsis. When someone suffers from a digestive motility disorder, these contractions are abnormal. This disorder can be due to one of two causes:
  • A problem within the muscle itself
  • A problem with the nerves or hormones that control the muscle's contractions
Intestinal walls consist of layers of muscles. In normal conditions, these muscles contract and relax in a coordinated, rhythmic fashion that propels food from the esophagus to the stomach, and through the intestine to the anus. But in the presence of a motility disorder, these contractions don't occur in a coordinated fashion. This results in food not passing through the intestine properly. When there is a motility disorder, the following symptoms may occur: Gastrointestinal motility disorders may be associated with the following conditions:
  • Irritable bowel syndrome
  • Diabetes
  • Gastroparesis — paralysis of the stomach
  • Esophageal spasms — irregular contractions of the muscles in the esophagus
  • Hirschsprung's disease — a congenital disorder in which poor motility causes obstruction of the large intestine
  • Chronic intestinal pseudo-obstruction — a rare disorder of the muscles and nerves in the intestine
  • Scleroderma — a progressive hardening and scarring of the skin and connective tissues
  • Achalasia — an esophageal motility disorder

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